Opioids may additionally induce worsening of pre-present central rest apnoea (see area four.8). Concomitant utilization of oxycodone and sedative medicines like benzodiazepines or related medicines may bring about sedation, respiratory despair, coma and death. As a consequence of these risks, concomitant prescribing Using these sedative medicines n

In advance of taking ROXICODONE, tell your healthcare company For those who have a history of: head injury, seizures Recommend the two people and caregivers about the threats of respiratory depression and sedation when ROXICODONE is utilized with benzodiazepines or other CNS depressants (which includes alcohol and illicit drugs). Suggest suffere